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The Poetry Fan Who Taught an LLM to Read and Write DNA
By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating biological design.
He’s Gleaning the Design Rules of Life to Re-Create It
Yizhi “Patrick” Cai is coordinating a global effort to write a complete synthetic yeast genome. If he succeeds, the resulting cell will be the artificial life most closely related to humans to date.
The Mystery of the Missing Multicellular Prokaryotes
Why have bacteria never evolved complex multicellularity? A new hypothesis suggests that it could come down to how prokaryotic genomes respond to a small population size.
Viruses Finally Reveal Their Complex Social Life
New research has uncovered a social world of viruses full of cheating, cooperation and other intrigues, suggesting that viruses make sense only as members of a community.
A ‘Lobby’ Where a Molecule Mob Tells Genes What to Do
Highly repetitive regions of junk DNA may be the key to a newly discovered mechanism for gene regulation.
The Year in Biology
In a year packed with fascinating discoveries, biologists pushed the limits of synthetic life, probed how organisms keep time, and refined theories about consciousness and emotional health.
Evolving Bacteria Can Evade Barriers to ‘Peak’ Fitness
Paradoxically, natural selection can sometimes seem to block organisms from evolving useful adaptations. But a new study of “fitness landscapes” and antibiotic resistance in bacteria shows that life still finds a way.
Andreas Wagner Pursues the Secrets to Evolutionary Success
Why did mammals, grasses and some other groups of organisms explode in diversity only after millions of years? The evolutionary biologist Andreas Wagner plumbs the secrets of those “sleeping beauties.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.