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Jennifer Doudna, one of CRISPR’s primary innovators, stays optimistic about how the gene-editing tool will continue to empower basic biological understanding.
If highly repetitive gene-regulating sequences in DNA are easily lost, that may explain why some adaptations evolve quickly and repeatedly.
How does evolution select the fittest “individuals” when they are ecosystems made up of hosts and their microbiomes? Biologist debate the need to revise theories.
Using a new CRISPR-based technique, researchers are examining how the position of DNA within the nucleus affects gene expression and cell function.
For the first time, researchers see how proteins grab loops of DNA and bundle them for cell division. The discovery also hints at how the genome folds to regulate gene expression.
Compact genomes and tiny cells gave flowering plants an edge over competing flora. This discovery hints at a broader evolutionary principle.
To discover our species’ deep history and to shape its future health, we should learn from the microbes that accompanied us on our evolutionary journey.
Preserving its DNA ought to be a cell’s top priority. But bacteria slow their DNA repair to a crawl in favor of proofreading gene transcripts.
An unexpected mechanism allows wasps to rapidly co-opt genes for new toxic functions.