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With a fully sequenced genome in hand, scientists hope they are finally poised to learn how axolotls regenerate lost body parts.
The more closely geneticists look at complex traits and diseases, the harder it gets to find active genes that don’t play some part in them.
Computer code serves as a useful analogy for what our genes do, but the complexity and messiness of life go well beyond simple analogies and mathematical models.
Can a set of simple instructions produce complex, three-dimensional living structures?
For the first time, researchers see how proteins grab loops of DNA and bundle them for cell division. The discovery also hints at how the genome folds to regulate gene expression.
Mitonuclear conflict — a struggle between the genes in a cell’s nucleus and its mitochondria — might sometimes split species in two.
How many Neanderthals were there? Archaeology and genetics have given very different answers. A new study reconciles them and reveals the lost history of these ancient people — including an early brush with extinction.
Researchers have used the gene-editing tool CRISPR to manipulate the way that DNA coils up inside the cell — another step in the quest to understand how the genome’s 3-D structure impacts its function.
Coils and twirls in DNA’s double-helix change how the molecule behaves, opening a new role for topology in the study of life.