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DNA

520px illustration of genome packaging
genomics

How Cells Pack Tangled DNA Into Neat Chromosomes

For the first time, researchers see how proteins grab loops of DNA and bundle them for cell division. The discovery also hints at how the genome folds to regulate gene expression.

Birds and mitonuclear conflict
evolution

Genetic Struggles Within Cells May Create New Species

Mitonuclear conflict — a struggle between the genes in a cell’s nucleus and its mitochondria — might sometimes split species in two.

Modern humans (at left) and Neanderthals (right)
evolution

Genetics Spills Secrets From Neanderthals’ Lost History

How many Neanderthals were there? Archaeology and genetics have given very different answers. A new study reconciles them and reveals the lost history of these ancient people — including an early brush with extinction.

genomics

Genetic Architects Untwist DNA’s Turns

Researchers have used the gene-editing tool CRISPR to manipulate the way that DNA coils up inside the cell — another step in the quest to understand how the genome’s 3-D structure impacts its function.

Biology

How Strange Twists in DNA Orchestrate Life

Coils and twirls in DNA’s double-helix change how the molecule behaves, opening a new role for topology in the study of life.