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The Joy of Why

Can We Program Our Cells?

By Steven Strogatz
March 8, 2023
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By genetically instructing cells to perform tasks that they wouldn’t in nature, synthetic biologists can learn deep secrets about how life works. Steven Strogatz discusses the potential of this young field with researcher Michael Elowitz.

A sad woman stands under an umbrella that is decorated with images of brains, molecules and DNA. Rain falls on her under the umbrella but the day is otherwise clear.
neuroscience

The Cause of Depression Is Probably Not What You Think

By Joanna Thompson
January 26, 2023
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Depression has often been blamed on low levels of serotonin in the brain. That answer is insufficient, but alternatives are coming into view and changing our understanding of the disease.

neuroscience

What Causes Alzheimer’s? Scientists Are Rethinking the Answer.

By Yasemin Saplakoglu
December 8, 2022
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After decades in the shadow of the reigning model for Alzheimer’s disease, alternative explanations are finally getting the attention they deserve.

A snake and two frogs staring at one another across a rock.
genomics

How Genes Can Leap From Snakes to Frogs in Madagascar

By Veronique Greenwood
October 27, 2022
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The discovery of a hot spot for horizontal gene transfer draws attention to the possible roles of parasites and ecology in such changes.

synthetic biology

Biologists Use Genetic Circuits to Program Plant Roots

By Joanna Thompson
September 28, 2022
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Using inserted genetic circuitry, synthetic biologists controlled the growth of plant roots for the first time.

The Joy of Why

Why Do We Get Old, and Can Aging Be Reversed?

By Steven Strogatz
July 27, 2022
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Everybody gets older, but not everyone ages in the same way. In this episode, Steven Strogatz speaks with Judith Campisi and Dena Dubal, two biomedical researchers who study the aging process.

Illustration of icons that relate to life’s origins: a volcano, molecules, a crab, fish, DNA and more.
The Joy of Why

How Could Life Evolve From Cyanide?

By Steven Strogatz
June 1, 2022
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How did life arise on Earth? Steven Strogatz speaks with the Nobel Prize-winning biologist Jack Szostak and Betül Kaçar, a paleogeneticist and astrobiologist, to explore our best understanding of how we all got here.

Artist’s illustration representing the immune system standing guard against a world of pathogens.
The Joy of Why

Why Is Inflammation a Dangerous Necessity?

By Steven Strogatz
April 20, 2022
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The immune system protects us from a full spectrum of pathogens, but without balance, it can end up hurting us over time, too. The immunologist Shruti Naik explains how our defenses can turn on us.

Video microscopy of a large C. elegans roundworm flanked by several much smaller ones.
evolution

In Sexy Worms, Inheritance Beyond Genes Can Help Evolution

By Carrie Arnold
April 19, 2022
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Traits from RNA molecules passed between multiple generations of worms can work with genetic changes to influence future evolution.


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