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Researchers have used the gene-editing tool CRISPR to manipulate the way that DNA coils up inside the cell — another step in the quest to understand how the genome’s 3-D structure impacts its function.
In a monumental set of experiments, spread out over nearly two decades, biologists removed genes two at a time to uncover the secret workings of the cell.
Gene drives promise to spread a trait across an entire population. But evolutionary forces are going to alter even the best-engineered plans.
The subtle mechanics of densely packed cells may help explain why some cancerous tumors stay put while others break off and spread through the body.
Metal-eating microbes get energy from rocks and could teach us about life on other worlds — but first scientists had to learn how to grow them in the lab.
Scientists have figured out how microbes can suck energy from rocks. Such lifeforms might be more widespread than anyone anticipated.
Scientists have created a synthetic organism that possesses only the genes it needs to survive. But they have no idea what roughly a third of those genes do.
Coils and twirls in DNA’s double-helix change how the molecule behaves, opening a new role for topology in the study of life.
Only a few genetic changes were enough to change an ordinary stomach bug into the bacteria responsible for the plague.