Biochemistry

In a hot spring at Yellowstone National Park, a microbe does something that life shouldn’t be able to do: It breathes oxygen and sulfur at the same time.

Rare and powerful compounds, known as keystone molecules, can build a web of invisible interactions among species.

Cell membranes from comb jellies reveal a new kind of adaptation to the deep sea: curvy lipids that conform to an ideal shape under pressure.

Drugs that target the neurotransmitter serotonin have long been prescribed to treat depression. Now the spotlight is turning to other aspects of brain chemistry. In this episode, the neuropharmacologist John Krystal shares findings that are overturning our understanding of depression.

The preferred “handedness” of biomolecules could have emerged from biased interactions between electrons and magnetic surfaces, new research suggests.

Depression has often been blamed on low levels of serotonin in the brain. That answer is insufficient, but alternatives are coming into view and changing our understanding of the disease.

Structural studies of the robust material called sporopollenin reveal how it made plants hardy enough to reproduce on dry land.

Benjamin List and David MacMillan received the 2021 Nobel Prize in Chemistry for their development of asymmetrical organocatalysis.

The DNA of some viruses doesn’t use the same four nucleotide bases found in all other life. New work shows how this exception is possible and hints that it could be more common than we think.