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Molecular biology

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Unexpected ‘Germline’ Plant Cells May Shield New Generations

August 5, 2019

To avoid passing on new mutations to offspring, plants may minimize the number of divisions by the stem cells that make flowers and seeds.

Ancient DNA Yields Snapshots of Vanished Ecosystems

May 29, 2019

Surviving fragments of genetic material preserved in sediments allow scientists to see the full diversity of past life — even microbes.

Biologists Discover Unknown Powers in Mighty Mitochondria

March 18, 2019

Mitochondria are most famous as sources of metabolic energy. But by splitting and combining, they can also release chemical signals to regulate cell activities, including the generation of neurons.

Q&A

Doudna’s Confidence in CRISPR’s Research Potential Burns Bright

February 27, 2019

Jennifer Doudna, one of CRISPR’s primary innovators, stays optimistic about how the gene-editing tool will continue to empower basic biological understanding.

Fragile DNA Enables New Adaptations to Evolve Quickly

February 5, 2019

If highly repetitive gene-regulating sequences in DNA are easily lost, that may explain why some adaptations evolve quickly and repeatedly.

Theorists Debate How ‘Neutral’ Evolution Really Is

November 8, 2018

For 50 years, evolutionary theory has emphasized the importance of neutral mutations rather than adaptive ones at the level of DNA. Real genomic data challenges that assumption.

Scientists Learn the Ropes on Tying Molecular Knots

October 29, 2018

As chemists tie the most complicated molecular knot yet, biophysicists create a “periodic table” that describes what kinds of knots are possible.

DNA Analysis Reveals a Genus of Plants Hiding in Plain Sight

September 4, 2018

Gene-sequence data is changing the way that botanists think about their classification schemes. A recent name-change for a common houseplant resulted from the discovery that it belonged in an overlooked genus.

How Many Genes Do Cells Need? Maybe Almost All of Them

April 19, 2018

An ambitious study in yeast shows that the health of cells depends on the highly intertwined effects of many genes, few of which can be deleted together without consequence.

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