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Molecular biology

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Spreading the Word on a Possible Alzheimer’s Treatment

May 27, 2020

Neuroscientists could use brain waves to spur immune cells into action against the disease — but the process is almost too fantastic to believe.

Where Do New Genes Come From?

April 9, 2020

In their search for sources of genetic novelty, researchers find that some “orphan genes” with no obvious ancestors evolve out of junk DNA, contrary to old assumptions.

Inherited Learning? It Happens, but How Is Uncertain

October 16, 2019

Studies suggest that epigenetics allows some learned adaptive responses to be passed down to new generations. The question is how.

Unexpected ‘Germline’ Plant Cells May Shield New Generations

August 5, 2019

To avoid passing on new mutations to offspring, plants may minimize the number of divisions by the stem cells that make flowers and seeds.

Ancient DNA Yields Snapshots of Vanished Ecosystems

May 29, 2019

Surviving fragments of genetic material preserved in sediments allow scientists to see the full diversity of past life — even microbes.

Biologists Discover Unknown Powers in Mighty Mitochondria

March 18, 2019

Mitochondria are most famous as sources of metabolic energy. But by splitting and combining, they can also release chemical signals to regulate cell activities, including the generation of neurons.

Q&A

Doudna’s Confidence in CRISPR’s Research Potential Burns Bright

February 27, 2019

Jennifer Doudna, one of CRISPR’s primary innovators, stays optimistic about how the gene-editing tool will continue to empower basic biological understanding.

Fragile DNA Enables New Adaptations to Evolve Quickly

February 5, 2019

If highly repetitive gene-regulating sequences in DNA are easily lost, that may explain why some adaptations evolve quickly and repeatedly.

Theorists Debate How ‘Neutral’ Evolution Really Is

November 8, 2018

For 50 years, evolutionary theory has emphasized the importance of neutral mutations rather than adaptive ones at the level of DNA. Real genomic data challenges that assumption.