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Frank Wilczek has been at the forefront of theoretical physics for the past 50 years. He talks about winning the Nobel Prize for work he did as a student, his solution to the dark matter problem, and the God of a scientist.

Lauren Williams has charted an adventurous mathematical career out of the pieces of a fundamental object called the positive Grassmannian.

Has physics reached the limits of what we can discover — or are the possibilities only just beginning?

It has been thought of as many things: a pointlike object, an excitation of a field, a speck of pure math that has cut into reality. But never has physicists’ conception of a particle changed more than it is changing now.

We’ve created a new way to explore the fundamental constituents of the universe.

Our new series of articles explores the search for fundamental structure at the edge of science.

Renormalization has become perhaps the single most important advance in theoretical physics in 50 years.

Physicists have identified an algebraic structure underlying the messy mathematics of particle collisions. Some hope it will lead to a more elegant theory of the natural world.

Can we test speculations about how quantum physics affects black holes and the Big Bang?

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