The astrophysicist Joshua Frieman seeks to pinpoint the mysterious substance driving the accelerating expansion of the universe.

A massive statistical study suggests that even though genetic changes happen at random, the final evolutionary outcome — fitness — is predictable.

Nature’s large-scale patterns emerge from incomplete surveys that borrow ideas from information theory.

Newly discovered particles are forcing physicists to extend their simple picture of subatomic interactions or replace it with a more nuanced understanding.

Our bodies are a genetic patchwork, possessing variation from cell to cell. Is that a good thing?

Physicists have begun to explore the idea that mass and length may not be fundamental properties of nature. The hypothesis could help to avoid the conclusion that our world is just a weird bubble in an endlessly foaming multiverse.

Subhash Khot’s bold conjecture is helping mathematicians explore the precise limits of computation.

Martin Hairer was named a 2014 Fields medalist for an epic masterpiece in stochastic analysis that colleagues say “created a whole world.”

Maryam Mirzakhani, who became the first woman Fields medalist for drawing deep connections between topology, geometry and dynamical systems, has died of cancer at the age of 40. This is our 2014 profile of her life and work.