proteins

After decades in the shadow of the reigning model for Alzheimer’s disease, alternative explanations are finally getting the attention they deserve.

A new study reveals that bacteria can fight viruses in a surprisingly elegant way that has no known counterpart in more complex life.

Protein buildups like those seen around neurons in Alzheimer’s, Parkinson’s and other brain diseases occur in all aging cells, a new study suggests. Learning their significance may reveal new strategies for treating age-related diseases.

How did life arise on Earth? Steven Strogatz speaks with the Nobel Prize-winning biologist Jack Szostak and Betül Kaçar, a paleogeneticist and astrobiologist, to explore our best understanding of how we all got here.

RNA and peptides coevolving in the primordial world might have jointly served as a precursor to the modern ribosome.

The immune system protects us from a full spectrum of pathogens, but without balance, it can end up hurting us over time, too. The immunologist Shruti Naik explains how our defenses can turn on us.

Life could use a more expansive genetic code in theory, but new work shows that improving on three-letter codons would be a challenge.

The discovery that short peptides can form spontaneously on cosmic dust hints at more of a role for them in the earliest stages of life’s origin, on Earth or elsewhere.

The molecular signaling systems of complex cells are nothing like simple electronic circuits. The logic governing their operation is riotously complex — but it has advantages.