Proteins

Every second, hundreds to thousands of molecules move through thousands of nuclear pores in each of your cells. A new high-definition view reveals the machine in action.

Innovations in imaging and genetic engineering are coming together to probe the biophysics of cytoplasm inside living animals.

A collection of short dispatches from the field of climate microbiology conveys the contributions that single-celled life forms make to our climate system, and how we can work with them to address climate change.

Scientists have identified tubulin structures in primitive Asgard archea that may have been the precursor of our own cellular skeletons.

An updated evolutionary model shows that living systems evolve in a split-and-hit-the-gas dynamic, where new lineages appear in sudden bursts rather than during a long marathon of gradual changes.

How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals danger.

How do memories last a lifetime when the molecules that form them turn over within days, weeks or months? An interaction between two proteins points to a molecular basis for memory.

By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating biological design.

Biologists used artificial intelligence to make discoveries about molecules and the brain, and overturned long-held assumptions about the immune system and RNA.