Sleep

A popular hypothesis for how the brain clears molecular waste, which may help explain why sleep feels refreshing, is a subject of debate.

The reasons why sleep is so vital often hide in unexpected parts of the body, as host Steven Strogatz discovers in conversations with researchers Dragana Rogulja and Alex Keene.

The detailed understanding of brains and multicellular bodies reached new heights this year, while the genomes of the COVID-19 virus and various organisms yielded more surprises.

Studies of sleep are usually neurological. But some of nature’s simplest animals suggest that sleep evolved for metabolic reasons, long before brains even existed.

Anesthesia is very different from sleep — which is why it offers unique opportunities for studying the human brain, says the physician-researcher and statistician Emery Brown.

By digging out signals hidden within the brain’s electrical chatter, scientists are getting new insights into sleep, aging and more.

While the study of the SARS-CoV-2 virus was the most urgent priority, biologists also learned more about how brains process information, how to define individuality and why sleep deprivation kills.

Going without sleep for too long kills animals but scientists haven’t known why. Newly published work suggests that the answer lies in an unexpected part of the body.

An organized tide of brain waves, blood and spinal fluid pulsing through a sleeping brain may flush away neural toxins that cause Alzheimer’s and other diseases.