Metabolism

New research makes a molecular connection between the brain and aging — and shows that overactive neurons can shorten life span.

Cells in symbiotic partnership, sometimes nested one within the other and functioning like organelles, can borrow from their host’s genes to complete their own metabolic pathways.

Mitochondria are most famous as sources of metabolic energy. But by splitting and combining, they can also release chemical signals to regulate cell activities, including the generation of neurons.

A computational study reveals surprising flexibility hidden within metabolic networks, providing new evidence for an evolutionary concept called exaptation.