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Metabolism

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The Microbial Masters of Earth’s Climate

September 15, 2025

A collection of short dispatches from the field of climate microbiology conveys the contributions that single-celled life forms make to our climate system, and how we can work with them to address climate change.

Q&A

The Pursuit of Life Where It Seems Unimaginable

August 20, 2025

A decade ago, Karen Lloyd discovered single-celled microbes living beneath the seafloor. Now she studies how they can survive in Earth’s crust, possibly for hundreds or thousands of years, and push life’s limits of time and energy.

The Cells That Breathe Two Ways

July 23, 2025

In a hot spring at Yellowstone National Park, a microbe does something that life shouldn’t be able to do: It breathes oxygen and sulfur at the same time.

How Much Energy Does It Take To Think?

June 4, 2025

Studies of neural metabolism reveal our brain’s effort to keep us alive and the evolutionary constraints that sculpted our most complex organ.

‘Turbocharged’ Mitochondria Power Birds’ Epic Migratory Journeys

May 19, 2025

Slight changes in the number, shape, efficiency and interconnectedness of organelles in the cells of flight muscles provide extra energy for birds’ continent-spanning feats.

How a Biofilm’s Strange Shape Emerges From Cellular Geometry

April 21, 2025

Micro decisions can have macro consequences. A soft matter physicist reveals how interactions within simple cellular collectives can lead to emergent physical traits.

The Mysterious Flow of Fluid in the Brain

March 26, 2025

A popular hypothesis for how the brain clears molecular waste, which may help explain why sleep feels refreshing, is a subject of debate.

How Metabolism Can Shape Cells’ Destinies

March 21, 2025

A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — plays a vital, overlooked role in the first steps of life.

How Does Life Happen When There’s Barely Any Light?

January 29, 2025

Under the sea ice during the Arctic’s pitch-black polar night, cells power photosynthesis on the lowest light levels ever observed in nature.

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