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Lab-Grown Human Cells Form Working Circuits in Rat Brains
Letting human brain organoids grow in animal brains could be an ethical new option for experimental studies of neurological disorders.
Embryo Cells Set Patterns for Growth by Pushing and Pulling
Patterns that guide the development of feathers and other features can be set by mechanical forces in the embryo, not just by gradients of chemicals.
Simple Gene Circuits Hint at How Stem Cells Find New Identities
Synthetic biology experiments suggest a “MultiFate” model for how genetically identical cells become the many different types found in complex organisms like us.
Cells Blaze Their Own Trails to Navigate Through the Body
With self-generated gradients of chemicals and physical tension, cells in the body steer themselves to vital destinations.
Flying Fish and Aquarium Pets Yield Secrets of Evolution
New studies reveal the ancient, shared genetic “grammar” underpinning the diverse evolution of fish fins and tetrapod limbs.
Mathematical Analysis of Fruit Fly Wings Hints at Evolution’s Limits
A painstaking study of wing morphology shows both the striking uniformity of individuals in a species and a subtle pattern of linked variations that evolution can exploit.
Biologists Rethink the Logic Behind Cells’ Molecular Signals
The molecular signaling systems of complex cells are nothing like simple electronic circuits. The logic governing their operation is riotously complex — but it has advantages.
How Do New Organs Evolve? A Beetle Gland Shows the Way.
The evolution of a defensive gland in beetles shows how organs can arise from novel cells carving out new functional niches for their neighbors.
New Genomic Study of Placenta Finds Deep Links to Cancer
A patchwork of genomic differences in the placenta may explain the organ’s “live fast, die young” strategy and its connections to cancer.